Emergent Role of the Fractalkine Axis in Dissemination of Peritoneal Metastasis from Epithelial Ovarian Carcinoma

@inproceedings{Main2017EmergentRO,
  title={Emergent Role of the Fractalkine Axis in Dissemination of Peritoneal Metastasis from Epithelial Ovarian Carcinoma},
  author={Hilal Gurler Main and Jia Xie and Goda G. Muralidhar and Osama Elfituri and Haoliang Xu and Andr{\'e} A. Kajdacsy-Balla and Maria V. Barbolina},
  booktitle={Oncogene},
  year={2017}
}
Epithelial ovarian carcinoma is the most common cause of death from gynecologic cancers largely due to advanced, relapsed and chemotherapy-resistant peritoneal metastasis, which is refractory to the currently used treatment approaches. Mechanisms supporting advanced and relapsed peritoneal metastasis are largely unknown, precluding development of more effective targeted therapies. In this study, we investigated the function of a potentially targetable fractalkine axis in the formation and the… CONTINUE READING