Emergence of primate genes by retrotransposon-mediated sequence transduction.

@article{Xing2006EmergenceOP,
  title={Emergence of primate genes by retrotransposon-mediated sequence transduction.},
  author={Jinchuan Xing and Hui Wang and Victoria P. Belancio and Richard Cordaux and Prescott L Deininger and Mark A Batzer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 47},
  pages={
          17608-13
        }
}
Gene duplication is one of the most important mechanisms for creating new genes and generating genomic novelty. Retrotransposon-mediated sequence transduction (i.e., the process by which a retrotransposon carries flanking sequence during its mobilization) has been proposed as a gene duplication mechanism. L1 exon shuffling potential has been reported in cell culture assays, and two potential L1-mediated exon shuffling events have been identified in the genome. SVA is the youngest… CONTINUE READING

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