Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease.

@article{Polhemus2014EmergenceOH,
  title={Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease.},
  author={David J. Polhemus and David Joseph Lefer},
  journal={Circulation research},
  year={2014},
  volume={114 4},
  pages={730-7}
}
Long recognized as a malodorous and highly toxic gas, recent experimental studies have revealed that hydrogen sulfide (H2S) is produced enzymatically in all mammalian species including man and exerts several critical actions to promote cardiovascular homeostasis and health. During the past 15 years, scientists have determined that H2S is produced by 3 endogenous enzymes and exerts powerful effects on endothelial cells, smooth muscle cells, inflammatory cells, mitochondria, endoplasmic reticulum… CONTINUE READING
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