Emergence of high-level mupirocin resistance in coagulase-negative staphylococci associated with increased short-term mupirocin use.

@article{Bathoorn2012EmergenceOH,
  title={Emergence of high-level mupirocin resistance in coagulase-negative staphylococci associated with increased short-term mupirocin use.},
  author={Erik Bathoorn and David J. Hetem and Jeriela Alphenaar and Johannes G Kusters and Marc Bonten},
  journal={Journal of clinical microbiology},
  year={2012},
  volume={50 9},
  pages={2947-50}
}
In our hospital, mupirocin has increasingly been used for peri-operative decolonization of Staphylococcus aureus. The target for mupirocin is isoleucyl tRNA synthetase (ileS). High-level resistance to mupirocin is conferred by acquisition of plasmids expressing a distinct ileS gene (ileS2). Here we evaluated the longitudinal trends in high-level mupirocin resistance in coagulase-negative staphylococci (CoNS) and linked this to the presence of ileS2 genes and mupirocin use. We assessed mupirocin… CONTINUE READING
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Mupirocin resistance

  • M Rahman, S Connolly, WC Noble, B Cookson, I Phillips
  • Clin . Infect . Dis .
  • 2009

High frequencies of clindamycin and tetracycline resistance in methicillin-resistant Staphylococcus aureus pulsed-field type USA300 isolates collected at a Boston ambulatory health center

  • LL Han
  • J. Clin. Microbiol
  • 2007
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