Emergence of central nervous system myeloma in the era of novel agents.

  title={Emergence of central nervous system myeloma in the era of novel agents.},
  author={Shane A Gangatharan and Dennis A. Carney and H Miles Prince and Max M Wolf and Elchanan H Januszewicz and D. Stuart Ritchie and Simon J Harrison},
  journal={Hematological oncology},
  volume={30 4},
Although multiple myeloma (MM) remains an incurable disease, considerable improvements in survival have been made with the introduction of autologous stem cell transplantation and new drugs. Central nervous system (CNS) MM is a rare complication associated with poor survival. Historically, CNS disease developed early in the course of MM; however recently, patients often present with CNS disease following multiple lines of therapy. It is hypothesized that exposure to novel agents (thalidomide… CONTINUE READING
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