Emergence of antitumor cytolytic T cells is associated with maintenance of hematologic remission in children with acute myeloid leukemia.

@article{Montagna2006EmergenceOA,
  title={Emergence of antitumor cytolytic T cells is associated with maintenance of hematologic remission in children with acute myeloid leukemia.},
  author={Daniela Montagna and Rita Maccario and Franco Locatelli and Enrica Montini and Sara Pagani and Federico Bonetti and Liane Daudt and Ilaria Turin and Daniela Lisini and Claudio Garavaglia and Paolo Dellabona and Giulia Casorati},
  journal={Blood},
  year={2006},
  volume={108 12},
  pages={3843-50}
}
Although the graft-versus-leukemia effect of allogeneic bone marrow transplantation (BMT) is of paramount importance in the maintenance of disease remission, the role played by the autologous T-cell response in antitumor immune surveillance is less defined. We evaluated the emergence of antileukemia cytotoxic T-lymphocyte precursors (CTLp's) and the correlation of this phenomenon with maintenance of hematologic remission in 16 children with acute myeloid leukemia (AML), treated with either… CONTINUE READING
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GIMEMAAIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children

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