Emergence of an invasive clone of nontoxigenic Corynebacterium diphtheriae in the urban poor population of Vancouver, Canada.

@article{Romney2006EmergenceOA,
  title={Emergence of an invasive clone of nontoxigenic Corynebacterium diphtheriae in the urban poor population of Vancouver, Canada.},
  author={Marc G. Romney and Diane L. Roscoe and Kathryn Bernard and Sik-to Thomas Lai and Androulla Efstratiou and A. M. T. Clarke},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 5},
  pages={1625-9}
}
Invasive disease due to Corynebacterium diphtheriae is rare in North America. Here we describe the emergence of a predominant clone of a nontoxigenic strain of C. diphtheriae in the impoverished population of Vancouver's downtown core. This clone has caused significant morbidity and contributed to at least two deaths. Over a 5-year period, seven cases of bacteremia due to C. diphtheriae were detected in patients admitted to Vancouver hospitals. Injection drug use, diabetes mellitus, skin… CONTINUE READING

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