Emergence of Scaffold-Free Approaches for Tissue Engineering Musculoskeletal Cartilages

@article{Duraine2014EmergenceOS,
  title={Emergence of Scaffold-Free Approaches for Tissue Engineering Musculoskeletal Cartilages},
  author={Grayson Duraine and Wendy E. Brown and Jerry C Hu and Kyriacos A. Athanasiou},
  journal={Annals of Biomedical Engineering},
  year={2014},
  volume={43},
  pages={543-554}
}
This review explores scaffold-free methods as an additional paradigm for tissue engineering. Musculoskeletal cartilages—for example articular cartilage, meniscus, temporomandibular joint disc, and intervertebral disc—are characterized by low vascularity and cellularity, and are amenable to scaffold-free tissue engineering approaches. Scaffold-free approaches, particularly the self-assembling process, mimic elements of developmental processes underlying these tissues. Discussed are various… CONTINUE READING
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