Emergence of Orai3 activity during cardiac hypertrophy.

  title={Emergence of Orai3 activity during cardiac hypertrophy.},
  author={Youakim Saliba and Mathilde Keck and Alexandre Marchand and Fabrice Atassi and Aude Ouill{\'e} and Olivier Cazorla and Mohamed Trebak and Catherine Pavoine and Alain Lacampagne and J. C. Hulot and Nassim Fares and J{\'e}r{\'e}my Fauconnier and A. M. Lompr{\'e}},
  journal={Cardiovascular research},
  volume={105 3},
AIMS Stromal interaction molecule 1 (STIM1) has been shown to control a calcium (Ca(2+)) influx pathway that emerges during the hypertrophic remodelling of cardiomyocytes. Our aim was to determine the interaction of Orai1 and Orai3 with STIM1 and their role in the constitutive store-independent and the store-operated, STIM1-dependent, Ca(2+) influx in… CONTINUE READING