Emergence of NDM-producing Klebsiella pneumoniae and Escherichia coli in Spain: phylogeny, resistome, virulence and plasmids encoding blaNDM-like genes as determined by WGS.

@article{PrezVzquez2019EmergenceON,
  title={Emergence of NDM-producing Klebsiella pneumoniae and Escherichia coli in Spain: phylogeny, resistome, virulence and plasmids encoding blaNDM-like genes as determined by WGS.},
  author={M. P{\'e}rez-V{\'a}zquez and Pedro J. Sola Campoy and Adriana Ortega and V. Bautista and S. Monz{\'o}n and G. Ru{\'i}z-Carrascoso and J. Mingorance and Eva M. Gonz{\'a}lez‐Barber{\'a} and C. Gimeno and B. Aracil and D. S{\'a}ez and N. Lara and S. Fern{\'a}ndez and J. J. Gonz{\'a}lez-L{\'o}pez and J. Campos and R. Kingsley and G. Dougan and J. Oteo-Iglesias},
  journal={The Journal of antimicrobial chemotherapy},
  year={2019}
}
OBJECTIVES NDM carbapenemases have spread worldwide. However, little information exists about the impact of NDM-producing Enterobacteriaceae in Spain. By WGS, we sought to elucidate the population structure of NDM-like-producing Klebsiella pneumoniae and Escherichia coli in Spain and to determine the plasmids harbouring blaNDM-like genes. METHODS High-resolution SNP typing, core-genome MLST and plasmid reconstruction (PlasmidID) were performed on 59 NDM-like-producing K. pneumoniae and 8 NDM… Expand
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