Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism

Abstract

BACKGROUND Resistance to triazoles was recently reported in Aspergillus fumigatus isolates cultured from patients with invasive aspergillosis. The prevalence of azole resistance in A. fumigatus is unknown. We investigated the prevalence and spread of azole resistance using our culture collection that contained A. fumigatus isolates collected between 1994… (More)
DOI: 10.1371/journal.pmed.0050219

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