Emergence and dissemination of a linezolid-resistant Staphylococcus capitis clone in Europe.

  title={Emergence and dissemination of a linezolid-resistant Staphylococcus capitis clone in Europe.},
  author={Marine Butin and Patr{\'i}cia Martins-Sim{\~o}es and Bruno Pichon and David Leyssene and S Bordes-Couecou and H{\'e}l{\'e}ne Meugnier and Caroline Rouard and Nadine Lema{\^i}tre and Fr{\'e}d{\'e}ric Schramm and Angela M. Kearns and Iris Spiliopoulou and H-L Hyyryl{\"a}inen and Oana Dumitrescu and François Vandenesch and C{\'e}line Dupieux and Fr{\'e}d{\'e}ric Laurent},
  journal={The Journal of antimicrobial chemotherapy},
  volume={72 4},
Objectives We investigated the epidemiological, clinical, microbiological and genetic characteristics of linezolid-resistant (LZR) Staphylococcus capitis isolates from French ICUs, and compared them with LZR S. capitis isolates from other European countries. Methods All LZR isolates were subjected to antimicrobial susceptibility testing (AST) and the presence of cfr and optrA genes as well as mutations in the 23S rRNA and ribosomal proteins were investigated using specific PCR with sequencing… CONTINUE READING
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