Embryotropic effect of insulin-like growth factor (IGF)-I and its receptor on development of porcine preimplantation embryos produced by in vitro fertilization and somatic cell nuclear transfer.

@article{Kim2005EmbryotropicEO,
  title={Embryotropic effect of insulin-like growth factor (IGF)-I and its receptor on development of porcine preimplantation embryos produced by in vitro fertilization and somatic cell nuclear transfer.},
  author={Sue Youn Kim and Gab Sang Lee and So Hyun Lee and Hye Soo Kim and Yeon Woo Jeong and Ji Hye Kim and Sung keun Kang and Byung Chun Lee and Woo Suk Hwang},
  journal={Molecular reproduction and development},
  year={2005},
  volume={72 1},
  pages={88-97}
}
Insulin-like growth factor (IGF)-I is a receptor-mediated autocrine/paracrine growth/survival factor for mammalian embryo development. The present study investigated the temporal expression and regulation of porcine IGF-I receptor (IGF-IR) mRNA and the role of IGF-I on development of porcine in vitro fertilized (IVF) and somatic cell nuclear transfer (SCNT) embryos. As assessed by semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR), the level of IGF-IR mRNA expression was… CONTINUE READING