Embryotoxicity of silver ions is diminished by ceruloplasmin—further evidence for its role in the transport of copper

@article{Shavlovski1995EmbryotoxicityOS,
  title={Embryotoxicity of silver ions is diminished by ceruloplasmin—further evidence for its role in the transport of copper},
  author={Mikhail M. Shavlovski and Nicolai A. Chebotar and Liudmila A. Konopistseva and Elena T. Zakharova and Anatoliy M. Kachourin and Vadim B. Vassiliev and V. Gaitskhoki},
  journal={Biometals},
  year={1995},
  volume={8},
  pages={122-128}
}
The effect of alimentary administration of silver salts upon embryogenesis in rats was studied. Feeding of female rats throughout the term on a regular diet supplemented with AgCl did not cause alterations of their physiological functions, despite the fact that enzymatically active copper-containing ceruloplasmin (CP) was eliminated from the blood plasma. However, developmental abnormalities of embryos, their prenatal death or the 100% mortality of the newborns in the first 24 h of life was… CONTINUE READING

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