Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.


Rat postimplantation whole-embryo culture (WEC) is a promising alternative test for the assessment of developmental toxicity. Toxicogenomic-based approaches may improve the predictive ability of the WEC model by providing a means to identify compound-specific mechanistic responses associated with embryotoxicity in vivo. Furthermore, alterations in gene… (More)
DOI: 10.1093/toxsci/kfq292


6 Figures and Tables