Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine

Abstract

Embryonic stem (ES) cells are of great interest as a model system for studying early developmental processes and because of their potential therapeutic applications in regenerative medicine. Obtaining a systematic understanding of the mechanisms that control the 'stemness' - self-renewal and pluripotency - of ES cells relies on high-throughput tools to… (More)
DOI: 10.1186/gm291

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