Embryonic salivary gland epithelial branching activity is experimentally independent of epithelial expansion activity.

@article{Bassett1989EmbryonicSG,
  title={Embryonic salivary gland epithelial branching activity is experimentally independent of epithelial expansion activity.},
  author={Kathlene E Bassett and Brian S. Spooner},
  journal={Developmental biology},
  year={1989},
  volume={133 2},
  pages={569-75}
}
Embryonic mouse submandibular salivary gland rudiments undergo morphogenesis in organ culture, characterized by extensive epithelial growth and expansion and repetitive branching activity. Tunicamycin, at a concentration of 25 ng/ml culture medium, decreases the degree of net protein accumulation by 83% and the degree of epithelial expansion by 70% compared to controls, over a 48-hr culture tenure. These decreases correlate with reduced incorporation of [3H]thymidine into DNA. Nevertheless… CONTINUE READING

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