Embryonic neurons transplanted into the tibial nerve reinnervate muscle and reduce atrophy but NCAM expression persists.

@article{Grumbles2008EmbryonicNT,
  title={Embryonic neurons transplanted into the tibial nerve reinnervate muscle and reduce atrophy but NCAM expression persists.},
  author={Robert M. Grumbles and Vania W Almeida and Christine K. Thomas},
  journal={Neurological research},
  year={2008},
  volume={30 2},
  pages={183-9}
}
OBJECTIVE The aim of this study was to use the glycogen depletion technique to determine whether reinnervated muscle fibers could be distinguished from denervated muscle fibers by their size or by neural cell adhesion molecule (NCAM) expression. METHODS Medial gastrocnemius muscles of five adult Fischer rats were reinnervated from embryonic neurons transplanted into the distal stump of the tibial nerve. Ten weeks later, the transplants were stimulated repeatedly to deplete reinnervated muscle… CONTINUE READING

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