Embryonic motor neuron dendrite growth is stunted by inhibition of nitric oxide-dependent activation of soluble guanylyl cyclase and protein kinase G.

@article{Xiong2007EmbryonicMN,
  title={Embryonic motor neuron dendrite growth is stunted by inhibition of nitric oxide-dependent activation of soluble guanylyl cyclase and protein kinase G.},
  author={Guoxiang Xiong and Jelena Mojsilovic-Petrovic and Cristi{\'a}n A. P{\'e}rez and Robert Gordon Kalb},
  journal={The European journal of neuroscience},
  year={2007},
  volume={25 7},
  pages={1987-97}
}
We have examined the participation of a neuronal nitric oxide synthase (nNOS) signaling pathway in the elaboration of motor neuron dendrites during embryonic life. During chick embryogenesis, nNOS is expressed by interneurons that surround the motor neuron pools in the ventral horn. Pseudorabies virus tracing suggests that these cells, while juxtaposed to motor neurons are not synaptically connected to them. The downstream effectors, soluble guanylyl cyclase (sGC) and protein kinase G (PKG… CONTINUE READING
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