Embryonic haemopoietic stem cell grafts in the treatment of murine genetic anaemia.

@article{Hollands1988EmbryonicHS,
  title={Embryonic haemopoietic stem cell grafts in the treatment of murine genetic anaemia.},
  author={P Hollands},
  journal={British journal of haematology},
  year={1988},
  volume={70 2},
  pages={157-63}
}
  • P Hollands
  • Published 1988 in British journal of haematology
Embryonic haemopoietic stem cells obtained from early post-implantation mouse embryos can be successfully used in the treatment of murine genetic anaemia. Anaemic recipients had either chronic macrocytic anaemia, which was lethal without treatment, or mild anaemia without increased mortality. All successfully grafted recipients developed donor haemoglobin and glucose phosphate isomerase electrophoretic markers, indicating the presence of donor erythrocytes and lymphocytes. The minimum number of… CONTINUE READING

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