Embryonic exposure to diclofenac disturbs actin organization and leads to myofibril misalignment.

Abstract

The objective of this study was to investigate the embryotoxicity of diclofenac. Zebrafish (Danio rerio) embryos at 12 hpf were treated with different dosages of diclofenac (0-2,000 ppm) for different time courses (12-72 hr). Results showed no evident differences in survival rates or morphological changes between the mock-treated control (0 ppm) zebrafish… (More)
DOI: 10.1002/bdrb.20292

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