Embryonic diapause: development on hold.

@article{Fenelon2014EmbryonicDD,
  title={Embryonic diapause: development on hold.},
  author={Jane C Fenelon and Arnab Banerjee and Bruce D. Murphy},
  journal={The International journal of developmental biology},
  year={2014},
  volume={58 2-4},
  pages={
          163-74
        }
}
Embryonic diapause, the temporary suspension of development of the embryo, is a fascinating reproductive strategy that has been frequently exploited across the animal kingdom. It is characterized by an arrest in development that occurs at the blastocyst stage in over 130 species of mammals. Its presumed function is to uncouple mating from parturition, to ensure that both occur at the most propitious moment for survival of the species. Diapause can be facultative, i.e. induced by physiological… 
Models of embryonic diapause in Carnivora
TLDR
It is not clear whether the regulatory mechanisms that have been identified in the better-known species are universal to carnivore diapause, but new studies have identified the uterine signals in the mink, and it has been shown that the synthesis and secretion of polyamines activates the minks embryo from diappause.
The enigma of embryonic diapause
TLDR
The complex embryo-uterine interactions that induce, maintain and reactivate the blastocyst from diapause are discussed, highlighting the roles of hormones, cytokines and growth factors across animal species.
Research advances on embryonic diapause in mammals.
TLDR
The present review summarizes the research advances related to embryonic diapause to enhance the understanding of this phenomenon and to be considered when there are future research endeavors related to this phenomenon.
Regulation of diapause in carnivores.
TLDR
The findings suggest that the polyamines, with synthesis under the control of pituitary prolactin, are the uterine factor whose absence is responsible for embryonic diapause in mustelid carnivores.
Mammalian Gestational Strategies: Embryonic Diapause and Pseudopregnancy
TLDR
The evolutionary advantage of diapause is that it allows the uncoupling of mating from parturition so that young are born under the most favorable conditions for survival.
Embryonic Diapause
Embryonic diapause in other words temporary cessation of embryonic development is a common some plant and animal species. Embryonic diapause is a temporary cessation of the development of
Uterine morphology during diapause and early pregnancy in the tammar wallaby (Macropus eugenii)
TLDR
Diapause, like pregnancy, is under unilateral endocrine control in the tammar, and that preparation for and maintenance of diapause requires substantial changes to uterine endometrial cell ultrastructure and activity.
Polyamine-Mediated Effects of Prolactin Dictate Emergence from Mink Obligate Embryonic Diapause1
TLDR
Results provide strong evidence that obligate diapause in vivo is caused by the paucity of polyamines necessary for activation of the embryo after prolactin-induced termination of diAPause.
The history of the discovery of embryonic diapause in mammals
TLDR
The history of the discovery of embryonic diapause in mammals, the key breakthroughs, the current understanding, and future directions for the field are described.
Could embryonic diapause facilitate conservation of endangered species?
TLDR
Detailed research on the pathways behind initiation and maintenance of the dormant state of a blastocyst should be the first priority to facilitate the introduction of embryonic diapause as a novel tool in assisted reproduction.
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