Embryonal carcinoma cells express Qa and Tla class I genes of the major histocompatibility complex.

@article{OstrandRosenberg1989EmbryonalCC,
  title={Embryonal carcinoma cells express Qa and Tla class I genes of the major histocompatibility complex.},
  author={Suzanne Ostrand-Rosenberg and Deborah A. Nickerson and Virginia K. Clements and Elizabeth P. Garcia and Esi S. N. Lamous{\'e}-Smith and Leroy Hood and Iwona Stroynowski},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1989},
  volume={86 13},
  pages={5084-8}
}
The murine major histocompatibility complex encodes H-2K and H-2D transplantation antigens and other class I-like proteins called Qa and Tla molecules; the functions of the Qa/Tla molecules are not known. That they may participate in embryonic cell-cell interactions and/or play a role in immune responses against tumors has been speculated. We have studied… CONTINUE READING