Embryo implantation and tumor metastasis: common pathways of invasion and angiogenesis.

@article{Murray1999EmbryoIA,
  title={Embryo implantation and tumor metastasis: common pathways of invasion and angiogenesis.},
  author={Michael J Murray and Bruce A. Lessey},
  journal={Seminars in reproductive endocrinology},
  year={1999},
  volume={17 3},
  pages={275-90}
}
Implantation of the embryo is one of the last great mysteries of reproductive biology. There are striking similarities present between the behavior of invasive placental cells and that of invasive cancer cells. In this review, we propose that cellular mechanisms used by the cells of the placenta during implantation are reused by cancer cells to invade and spread within the body. Integrins and other cell adhesion molecules, extracellular matrix and matrix metalloproteinases all appear to be… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 77 extracted citations

Malignant cancer and invasive placentation

Evolution, medicine, and public health • 2014
View 5 Excerpts
Highly Influenced

Trophoblast 'pseudo-tumorigenesis': Significance and contributory factors

Reproductive biology and endocrinology : RB&E • 2004
View 10 Excerpts
Highly Influenced

The history of the enzyme treatment of cancer.

Alternative therapies in health and medicine • 2014
View 3 Excerpts
Highly Influenced

Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b

Journal of cellular and molecular medicine • 2011
View 3 Excerpts
Highly Influenced

Role of microRNAs in embryo implantation

Reproductive biology and endocrinology : RB&E • 2017
View 1 Excerpt

Similar Papers

Loading similar papers…