Embryo collection induces transient activation of XBP1 arm of the ER stress response while embryo vitrification does not.

@article{Abraham2012EmbryoCI,
  title={Embryo collection induces transient activation of XBP1 arm of the ER stress response while embryo vitrification does not.},
  author={Tamara Abraham and Christopher L. Pin and Andrew J Watson},
  journal={Molecular human reproduction},
  year={2012},
  volume={18 5},
  pages={229-42}
}
Embryo cryopreservation has become a standard procedure in the practice of assisted reproduction. While routinely performed in IVF labs, the effects of embryo vitrification on the molecular mechanisms governing preimplantation development remain largely unknown. The endoplasmic reticulum stress (ER stress) response is an evolutionary conserved mechanism that cells employ to manage ER stress. ER stress can be defined as an imbalance between protein synthesis and secretion within the ER. The… CONTINUE READING
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