Embarking on a Chemical Space Odyssey.

Abstract

The chemical space explored in drug discovery programs is restricted by a narrow reaction toolkit and the frequent failure of even these reactions with polar and functionalized substrates. Recently, high-throughput reaction optimization has been integrated into discovery workflows, thereby increasing the value of specific reaction classes in the toolkit. It… (More)
DOI: 10.1021/acs.jmedchem.7b00423

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Cite this paper

@article{Chow2017EmbarkingOA, title={Embarking on a Chemical Space Odyssey.}, author={Shiao Y Chow and Adam Nelson}, journal={Journal of medicinal chemistry}, year={2017}, volume={60 9}, pages={3591-3593} }