Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use


Objectives:Irritable bowel syndrome with diarrhea (IBS-D) is often managed with over-the-counter therapies such as loperamide, though with limited success. This analysis evaluated the efficacy of eluxadoline in patients previously treated with loperamide in two phase 3 studies.Methods:Adults with IBS-D (Rome III criteria) were enrolled and randomized to… (More)
DOI: 10.1038/ajg.2017.72


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