Elucidation of three-dimensional ultrastructure of Hirano bodies by the quick-freeze, deep-etch and replica method

Abstract

To clarify the yet controversial fine structure of Hirano bodies, we made three-dimensional observations of the tissues from the right hippocampus obtained at autopsy of elderly patients by the quick-freeze, deep-etch and replica method. The basic structure of Hirano bodies was a unit lamella, a closely attached pair of sheets composed of parallel-running… (More)
DOI: 10.1007/BF00305865

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@article{Izumiyama1991ElucidationOT, title={Elucidation of three-dimensional ultrastructure of Hirano bodies by the quick-freeze, deep-etch and replica method}, author={Naotaka Izumiyama and Koushiro Ohtsubo and Takamitsu Tachikawa and H. Nakamura}, journal={Acta Neuropathologica}, year={1991}, volume={81}, pages={248-254} }