Elucidation of Akkermansia muciniphila Probiotic Traits Driven by Mucin Depletion

@inproceedings{Shin2019ElucidationOA,
  title={Elucidation of Akkermansia muciniphila Probiotic Traits Driven by Mucin Depletion},
  author={Jongoh Shin and Jung-Ran Noh and Dong-Ho Chang and Yong-Hoon Kim and Myung Hee Kim and Eaum Seok Lee and Suhyung Cho and Bon Jeong Ku and Moon-Soo Rhee and Byoung-Chan Kim and Chul-Ho Lee and Byung Kwan Cho},
  booktitle={Front. Microbiol.},
  year={2019}
}
Akkermansia muciniphila is widely considered a next-generation beneficial microbe. This bacterium resides in the mucus layer of its host and regulates intestinal homeostasis and intestinal barrier integrity by affecting host signaling pathways. However, it remains unknown how the expression of genes encoding extracellular proteins is regulated in response to dynamic mucosal environments. In this study, we elucidated the effect of mucin on the gene expression and probiotic traits of A… CONTINUE READING

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