Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells.

@article{Sze2007ElucidatingTS,
  title={Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells.},
  author={Siu Kwan Sze and Dominique P V de Kleijn and Ruenn Chai Lai and Eileen Khia Way Tan and Hui Zhao and Keng Suan Yeo and Teck Yew Low and Qizhou Lian and Chuen Neng Lee and Wayne Mitchell and Reida Menshawe El Oakley and Sai-Kiang Lim},
  journal={Molecular & cellular proteomics : MCP},
  year={2007},
  volume={6 10},
  pages={
          1680-9
        }
}
Transplantation of mesenchymal stem cells (MSCs) has been used to treat a wide range of diseases, and the mechanism of action is postulated to be mediated by either differentiation into functional reparative cells that replace injured tissues or secretion of paracrine factors that promote tissue repair. To complement earlier studies that identified some of the paracrine factors, we profiled the paracrine proteome to better assess the relevance of MSC paracrine factors to the wide spectrum of… CONTINUE READING

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