Elucidating the role of YAP in directing mesenchymal stem cell fate


Mesenchymal stem cells (MSCs) are a type of multipotent stem cell capable of differentiating into several cell types, including fat and bone cells. The Hippo pathway effectors TAZ and YAP have been implicated as important regulators of MSC fate, but their roles in this process are poorly understood. The goal of my thesis work was to illuminate the roles of… (More)


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