Elovl3: a model gene to dissect homeostatic links between the circadian clock and nutritional status.

@article{Anzulovich2006Elovl3AM,
  title={Elovl3: a model gene to dissect homeostatic links between the circadian clock and nutritional status.},
  author={Ana Anzulovich and Alain Mir and Michelle Brewer and Gabriela Ferreyra and Charles Vinson and Ruben Baler},
  journal={Journal of lipid research},
  year={2006},
  volume={47 12},
  pages={2690-700}
}
The ELOVL3 protein is a very long-chain fatty acid elongase found in liver, skin, and brown adipose tissues. Circadian expression of the Elovl3 gene in the liver is perturbed in mutant CLOCK mice but persists in mice with severe hepatic dysfunction. A reliance on an intact clock, combined with the refractoriness to liver decompensation and the finding of a… CONTINUE READING