Elongation factor Tu and the aminoacyl-tRNA-EFTu-GTP complex.

@article{Miller1974ElongationFT,
  title={Elongation factor Tu and the aminoacyl-tRNA-EFTu-GTP complex.},
  author={David Harry Miller and Herbert Weissbach},
  journal={Methods in enzymology},
  year={1974},
  volume={30},
  pages={
          219-32
        }
}
Publisher Summary The bacterial elongation factors EFTu and EFTs promote the binding of AA-tRNA to ribosomes via an AA-tRNA·EFTu·GTP intermediate. When this ternary complex interacts with ribosomes in the presence of messenger-RNA, the AA-tRNA is transferred to the ribosome and GTP is hydrolyzed with the formation of EFTu·GDP and P 1 . The EFTu·GDP complex dissociates very slowly. The function of EFTs is to catalyze the exchange of the tightly bound GDP with free GTP to form EFTu·GTP that can… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Time-Resolved Fluorescence Studies On Components Of The Prokaryotic Protein Elongation System

  • Photonics West - Lasers and Applications in Science and Engineering
  • 1988
VIEW 1 EXCERPT

The Genetic Mechanism and the Origin of Life

  • Springer US
  • 1978
VIEW 1 EXCERPT
CITES BACKGROUND