Elongation factor P restricts Salmonella’s growth by controlling translation of a Mg2+ transporter gene during infection

@inproceedings{Choi2017ElongationFP,
  title={Elongation factor P restricts Salmonella’s growth by controlling translation of a Mg2+ transporter gene during infection},
  author={Eunna Choi and Soomin Choi and Daesil Nam and Shinae Q. Park and Yoontak Han and Jung-shin Lee and Eun-Jin Lee},
  booktitle={Scientific reports},
  year={2017}
}
When a ribosome translates mRNA sequences, the ribosome often stalls at certain codons because it is hard to translate. Consecutive proline codons are such examples that induce ribosome stalling and elongation factor P (EF-P) is required for the stalled ribosome to continue translation at those consecutive proline codons. We found that EF-P is required for translation of the mgtB gene encoding a Mg2+ transporter in the mgtCBR virulence operon from the intracellular pathogen Salmonella enterica… CONTINUE READING
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