Elongation factor G participates in ribosome disassembly by interacting with ribosome recycling factor at their tRNA-mimicry domains.

@article{Ito2002ElongationFG,
  title={Elongation factor G participates in ribosome disassembly by interacting with ribosome recycling factor at their tRNA-mimicry domains.},
  author={Koichi Ito and Toshinobu Fujiwara and Tomohiko Toyoda and Yoshikazu Nakamura},
  journal={Molecular cell},
  year={2002},
  volume={9 6},
  pages={1263-72}
}
Elongation factor G (EF-G) is a G protein with motor function that drives two target molecules, a tRNA in the translating ribosome and the ribosome recycling factor (RRF) in the post-termination complex. How G protein motor action is transmitted to RRF is unknown. Thermus thermophilus RRF is nonfunctional in Escherichia coli. It became functional upon introducing a plasmid expressing E. coli EF-G with surface changes in its tRNA-mimic domain or by replacing the E. coli EF-G tRNA-mimic domain by… CONTINUE READING

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