Elongation factor EF-1 delta, a new target for maturation-promoting factor in Xenopus oocytes.

@article{MulnerLorillon1994ElongationFE,
  title={Elongation factor EF-1 delta, a new target for maturation-promoting factor in Xenopus oocytes.},
  author={Odile Mulner-Lorillon and O Minella and Patrick Cormier and J. P. Capony and Jean-claude Cavadore and Janine M. Morales and Robert Poulhe and Robert Bell{\'e}},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 31},
  pages={20201-7}
}
A new physiological target for Cdc2 protein kinase has been identified. It corresponds to a protein EF-1 delta, a constituent of the nucleotide exchange factor EF-1 beta gamma delta, involved in the elongation step of protein synthesis. EF-1 delta is phosphorylated by Cdc2 kinase on threonine and serine residues. Threonine has been identified as Thr122 in the sequence VQVTPAAK. During oocyte maturation, Thr122 is phosphorylated at metaphase, when p34cdc2 is active. Phosphorylation studies… CONTINUE READING

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