Elongation factor 2-specific calcium and calmodulin dependent protein kinase III activity in rat livers varies with age and calorie restriction.

@article{Riis1993ElongationF2,
  title={Elongation factor 2-specific calcium and calmodulin dependent protein kinase III activity in rat livers varies with age and calorie restriction.},
  author={Bent Riis and Suresh I S Rattan and Kristian Palmquist and {\AA}ke Nilsson{\AA}. Nilsson and Odd Erik Nyg{\aa}rd and Brian F. C. Clark},
  journal={Biochemical and biophysical research communications},
  year={1993},
  volume={192 3},
  pages={
          1210-6
        }
}
Elongation factors involved in polypeptide chain elongation are considered to be rate limiting for the slowing down of total protein synthesis during ageing. The activities of elongation factors are themselves regulated by various means, including phosphorylation. Here we have compared the activity of a protein kinase, called calcium- and calmodulin-dependent protein kinase III (CaM PK III), specific for the phosphorylation of elongation factor eEF-2, in cell-free extracts prepared from livers… CONTINUE READING
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