Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons

@inproceedings{Heise2014ElongationFP,
  title={Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons},
  author={Christopher Heise and Fabrizio Gardoni and Lorenza Culotta and Monica di Luca and Chiara Verpelli and Carlo Sala},
  booktitle={Front. Cell. Neurosci.},
  year={2014}
}
Neuronal activity results in long lasting changes in synaptic structure and function by regulating mRNA translation in dendrites. These activity dependent events yield the synthesis of proteins known to be important for synaptic modifications and diverse forms of synaptic plasticity. Worthy of note, there is accumulating evidence that the eukaryotic Elongation Factor 2 Kinase (eEF2K)/eukaryotic Elongation Factor 2 (eEF2) pathway may be strongly involved in this process. Upon activation, eEF2K… CONTINUE READING
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