Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting

@article{Qutub2008ElongationP,
  title={Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting},
  author={Amina A. Qutub and Aleksander S. Popel},
  journal={BMC Systems Biology},
  year={2008},
  volume={3},
  pages={13 - 13}
}
Angiogenesis, the growth of capillaries from preexisting blood vessels, has been extensively studied experimentally over the past thirty years. Molecular insights from these studies have lead to therapies for cancer, macular degeneration and ischemia. In parallel, mathematical models of angiogenesis have helped characterize a broader view of capillary network formation and have suggested new directions for experimental pursuit. We developed a computational model that bridges the gap between… CONTINUE READING
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