Ellobius lutescens: Sex Determination and Sex Chromosome

@article{Just2007EllobiusLS,
  title={Ellobius lutescens: Sex Determination and Sex Chromosome},
  author={Walter Just and Annette Baumstark and A. S{\"u}ss and Alexander S. Graphodatsky and Willem Rens and N. Sch{\"a}fer and Irina Bakloushinskaya and H. Hameister and Walther Vogel},
  journal={Sexual Development},
  year={2007},
  volume={1},
  pages={211 - 221}
}
The mole vole Ellobius lutescens is an interesting animal, not only concerning its sex determination mechanism without the Y-chromosomal Sry gene, that triggers sex determination in nearly all other mammalian species, but also regarding the karyotype with an odd number of chromosomes, being identical in male and female animals. The odd chromosome represents the X chromosome, and therefore, even males do not have a Y chromosome. We present an overview of a search for candidate genes of male sex… 
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Another way of looking at the enigma of sex determination in Ellobius lutescens
morphology, with the same odd number (2n = 17) being present in both sexes3. The odd chromosome is the X chromosome, and it constitutes approximately 5% of the haploid genome. It therefore appears
The sex determination in Ellobius lutescens remains bizarre
TLDR
This report provides key data on the genomic level that there are no coarse differences in the genomes of male and female animals by comparative genomic hybridization and provides evidence by linkage analysis in two E. lutescens pedigrees that Nr5a1 is not the key male sex-determining gene in Ellobius lutecens.
Ellobius lutescens, Th. (Rodentia, Microtinae): Q-, R-, and replication banding, patterns
TLDR
In the female studied, one chromosome 1 differs from those of the males by a marked elongation of a proximal euchromatic band in the long arm, and the female seems to represent the heterogametic sex.
Characterization of Pisrt1/Foxl2 in Ellobius lutescens and exclusion as sex-determining genes
TLDR
This work cloned and characterized two genes of the PIS (polled intersex syndrome) gene interval, which were reported as candidates in female-to-male sex reversal in hornless goats recently, and excluded linkage of Foxl2 and Pisrt1 loci with the sex of the animals.
Chromosome 9 of Ellobius lutescens is the X chromosome
TLDR
It is concluded that E. lutescens should be an ideal tool for testing candidate genes assumed to be involved in primary sex determination, as it exhibits the typical features of an X chromosome in male meiosis.
Ellobius lutescens Th. (Rhodentia, Microtinae): Q-, R-, and replication banding patterns. Chromosome 1 polymorphism in the male and presumptive heterogamety in the female.
TLDR
In the female studied, one chromosome 1 differs from those of the males by a marked elongation of a proximal euchromatic band in the long arm, and the female seems to represent the heterogametic sex.
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The karyotype of the microtine Ellobius lutescens Th., was analysed using the G and Q banding techniques. One of the chromsomes of the first pair has the same bands in both sexes while the other
Further chromosomal studies onEllobius lutescens: Heteromorphism of chromosome No. 1 is not associated with sex determination
TLDR
No definite chromosomal basis for sex determination was found in Ellobius lutescens, which carries 17 chromosomes in both sexes.
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TLDR
Analysis of whole-mount SC preparations from males of three species of the genus Ellobius revealed the formation of a closed sex SC bivalent and showed some morphological differences in the axes of sex chromosomes at meiotic prophase I.
Male sex determination in the spiny rat Tokudaia osimensis (Rodentia: Muridae) is not Sry dependent
TLDR
This species is thus the second rodent genus described so far as lacking the mammalian sex-determining factor Sry, since two species of voles in the genus Ellobius display the same unusual feature.
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