Ellagic acid protects rat embryos in culture from the embryotoxic effects of N-methyl-N-nitrosourea.

@article{Frank1992EllagicAP,
  title={Ellagic acid protects rat embryos in culture from the embryotoxic effects of N-methyl-N-nitrosourea.},
  author={A. Frank and J. Collier and C. Forsyth and Y. Heur and G. Stoner},
  journal={Teratology},
  year={1992},
  volume={46 2},
  pages={
          109-15
        }
}
  • A. Frank, J. Collier, +2 authors G. Stoner
  • Published 1992
  • Biology, Medicine
  • Teratology
  • Ellagic acid is a naturally occurring plant phenol that has demonstrated anticarcinogenic and antimutagenic activity in several test systems. Given the common proposed etiopathogenic processes of mutagenesis, carcinogenesis, and teratogenesis induced by genotoxic chemicals, the present study was initiated to determine whether ellagic acid would protect rat embryos in culture from the teratogenic effects of N-methyl-N-nitrosourea (MNU). Ellagic acid alone (as used in these experiments; 50 microM… CONTINUE READING
    4 Citations

    References

    SHOWING 1-10 OF 38 REFERENCES
    Inhibition of N-methyl-N-nitrosourea-induced mutagenicity and DNA methylation by ellagic acid.
    • R. Dixit, B. Gold
    • Chemistry, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1986
    • 94
    • PDF
    Protection against 3-methylcholanthrene-induced skin tumorigenesis in Balb/C mice by ellagic acid.
    • 97