Ellagic acid normalizes mitochondrial outer membrane permeabilization and attenuates inflammation-mediated cell proliferation in experimental liver cancer.

@article{Srigopalram2014EllagicAN,
  title={Ellagic acid normalizes mitochondrial outer membrane permeabilization and attenuates inflammation-mediated cell proliferation in experimental liver cancer.},
  author={Srisesharam Srigopalram and Indira A. Jayraaj and Balasubramanian Kaleeswaran and Kuppusamy Balamurugan and Muthusamy Ranjithkumar and T. Senthil Kumar and Jae In Park and Ill-Sup Nou},
  journal={Applied biochemistry and biotechnology},
  year={2014},
  volume={173 8},
  pages={2254-66}
}
Despite great advances in our understanding of the molecular causes of liver cancer, significant gaps still remain in our knowledge of the disease pathogenesis and development of effective strategies for early diagnosis and treatment. The present study was conducted to evaluate the chemopreventive activity of ellagic acid (EA) against experimental liver cancer in rats. This is the first report that implies a possible role of EA in controlling liver cancer through activation of mitochondrial… CONTINUE READING