Corpus ID: 9002436

Ellagic Acid Protects the Brain Against 6-Hydroxydopamine Induced Neuroinflammation in a Rat Model of Parkinson’s Disease

@article{Farbood2015EllagicAP,
  title={Ellagic Acid Protects the Brain Against 6-Hydroxydopamine Induced Neuroinflammation in a Rat Model of Parkinson’s Disease},
  author={Y. Farbood and A. Sarkaki and Mojtaba Dolatshahi and Seyed Mohammad Taqhi Mansouri and A. Khodadadi},
  journal={Basic and Clinical Neuroscience},
  year={2015},
  volume={6},
  pages={83 - 89}
}
Introduction: Neuroinflammation may play as an important risk factor in progressive degeneration of dopaminergic cells. Antioxidants have protective effects against free radicals-induced neural damage in Parkinson’s disease (PD). In the present study, we examined the effects of ellagic acid (EA) on locomotion and neuroinflammatory biomarkers in a rat model of PD induced by 6-hydroxidopamine (6-OHDA). Methods: 6-OHDA (16 μg/2 μl) was injected into the right medial forebrain bundle (MFB) in MFB… Expand
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