Elite swimmers and the D allele of the ACE I/D polymorphism

@article{Woods2001EliteSA,
  title={Elite swimmers and the D allele of the ACE I/D polymorphism},
  author={David Emmett Woods and Michelle Hickman and Yalda Jamshidi and David J. Brull and Vassilis Vassiliou and Alun M.C. Jones and Steve E Humphries and Hugh S. Irvine Montgomery},
  journal={Human Genetics},
  year={2001},
  volume={108},
  pages={230-232}
}
Abstract. A polymorphism of the human angiotensin-1-converting enzyme (ACE) gene has been identified in which the presence (insertion, I allele) of a 287-bp fragment rather than the absence (deletion, D allele) is associated with lower ACE activity. Several recent studies have shown an association of the I allele with endurance performance, it being found with excess frequency in elite distance runners, rowers and mountaineers. Other workers using heterogeneous cohorts of athletes from mixed… CONTINUE READING
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