Elimination of up to 80% of human pancreatic adenocarcinomas in athymic mice by cardiac hormones.

@article{Vesely2007EliminationOU,
  title={Elimination of up to 80% of human pancreatic adenocarcinomas in athymic mice by cardiac hormones.},
  author={David L. Vesely and Ehrentraud J. Eichelbaum and Ying Sun and Abdel A Alli and Brian A. Vesely and Stephen L Luther and William Gower},
  journal={In vivo},
  year={2007},
  volume={21 3},
  pages={445-51}
}
BACKGROUND Four cardiac hormones have anticancer effects in vitro: i) atrial natriuretic peptide (ANP), ii) vessel dilator, iii) long acting natriuretic peptide (LANP), and iv) kaliuretic peptide. MATERIALS AND METHODS These cardiac hormones were infused subcutaneously for 28 days with weekly fresh hormones at 3 nM min(-1) kg(-1) body weight in athymic mice bearing human pancreatic adenocarcinomas. RESULTS ANP, vessel dilator, LANP and kaliuretic peptide eliminated 80%, 33%, 20% and 14% of… CONTINUE READING
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