Elimination of the mycotoxin citrinin production in the industrial important strain Monascus purpureus SM001.

@article{Jia2010EliminationOT,
  title={Elimination of the mycotoxin citrinin production in the industrial important strain Monascus purpureus SM001.},
  author={Xiao Qin Jia and Zhi Nan Xu and Li ping Zhou and Chang Keun Sung},
  journal={Metabolic engineering},
  year={2010},
  volume={12 1},
  pages={
          1-7
        }
}
  • Xiao Qin Jia, Zhi Nan Xu, +1 author Chang Keun Sung
  • Published in Metabolic engineering 2010
  • Biology, Medicine
  • The application of the high-producing pigments industrial strain Monascus purpureus SM001 has been greatly limited by the synchronous production of mycotoxin citrinin. Here we have tried both traditional mutagenesis and metabolic engineering methods to eliminate the production of citrinin. Traditional chemical and physical mutagens were applied to induce mutagenesis, and a bio-screening method based on the antibacterial activity of citrinin against Bacillus subtilis was designed to select… CONTINUE READING

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