Elimination of syngeneic sarcomas in rats by a subset of T lymphocytes

@article{Fernandezcruz1980EliminationOS,
  title={Elimination of syngeneic sarcomas in rats by a subset of T lymphocytes},
  author={E Fernandez-cruz and Bruce A. Woda and Joseph D. Feldman},
  journal={The Journal of Experimental Medicine},
  year={1980},
  volume={152},
  pages={823 - 841}
}
Established subcutaneous Moloney sarcomas (MST-1) of large size and long duration were eliminated from syngeneic rats by intravenous infusion of varying numbers of specific syngeneic effector T lymphocytes. Spleen cells from BN rats in which tumor had regressed were cultured in an in vitro mixed lymphocyte tumor cell culture (MLTC) to augment cytotoxicity of effector cells. In the MLTC a T cell subset was expanded in response to MST-1 antigens and transformed into blast elements. With these… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 53 extracted citations

Immunotherapy of Melanoma

Springer International Publishing • 2016

Immunology of metastasis

Cancer and Metastasis Reviews • 2004

References

Publications referenced by this paper.
Showing 1-10 of 85 references

Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity. 3

J. E. Swerkosz, P. Marrack, J. W. Kappler
Exp. Med • 1979

Similar Papers

Loading similar papers…