Elimination of spatial interference in PRESS-localized editing spectroscopy.

  title={Elimination of spatial interference in PRESS-localized editing spectroscopy.},
  author={Lana G Kaiser and Karl Young and Gerald B. Matson},
  journal={Magnetic resonance in medicine},
  volume={58 4},
Unambiguous detection of gamma-amino butyric acid (GABA) in the human brain is hindered by low concentration and spectral overlap with other metabolites. The popular MEGA-PRESS (PRESS: point-resolved spectroscopic sequence) method allows spectral separation of GABA from other metabolites, but suffers from a significant signal-to-noise ratio (SNR) reduction due to the 4-compartment artifact. An alternative PRESS localization technique (PRESS+4) was investigated and compared to MEGA-PRESS using… CONTINUE READING


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