Elimination of hydrogen peroxide by Haemophilus somnus, a catalase-negative pathogen of cattle.

@article{Sample1991EliminationOH,
  title={Elimination of hydrogen peroxide by Haemophilus somnus, a catalase-negative pathogen of cattle.},
  author={A K Sample and Charles J. Czuprynski},
  journal={Infection and immunity},
  year={1991},
  volume={59 7},
  pages={2239-44}
}
Haemophilus somnus is a catalase-negative, gram-negative pathogen of cattle which is refractory to killing by bovine neutrophils. In this report, we showed that H. somnus rapidly inhibited Luminol-dependent chemiluminescence of bovine neutrophils costimulated with opsonized zymosan or phorbol myristate acetate. We have postulated that this inhibition resulted in part from H. somnus preventing the accumulation of hydrogen peroxide (H2O2) during the oxidative burst. In support of this hypothesis… CONTINUE READING