Elimination of asialofetuin and asialoorosomucoid by the intact rat. Quantitative aspects of the hepatic clearance mechanism.

@article{Regoeczi1978EliminationOA,
  title={Elimination of asialofetuin and asialoorosomucoid by the intact rat. Quantitative aspects of the hepatic clearance mechanism.},
  author={Erwin Regoeczi and M. T. Debanne and Mark W. C. Hatton and Aleksander Koj},
  journal={Biochimica et biophysica acta},
  year={1978},
  volume={541 3},
  pages={372-84}
}
The capacity of the liver to eliminate asialofetuin and asialoorosomucoid was investigated in intact rats. From plasma radioactivity curve measurements and assays on tissue homogenates the liver is shown to be able to dispose of an average of 19.8 microgram of asialofetuin/min per 100 g body weight. No other major route is identified for the disappearance… CONTINUE READING